Poultry coccidiosis, caused by protozoan parasites of the genus Eimeria, represents a significant threat to the global poultry industry due to its economic impact on production efficiency, high morbidity, and potential mortality. This research group aims to investigate the epidemiology, pathogenesis, and control strategies of coccidiosis in commercial and backyard poultry systems. Our work focuses on understanding host-parasite interactions, identifying genetic and environmental factors influencing disease susceptibility, and evaluating current and novel prophylactic measures, including anticoccidial drugs, vaccines, and alternative therapeutics. Recent studies have explored the efficacy of herbal extracts, probiotics, and improved management practices as sustainable approaches to disease control. Additionally, we employ advanced molecular techniques, including transcriptomics and proteomics, to uncover the mechanisms of host immunity and parasite resistance. Our findings contribute to developing integrated control programs that align with sustainable poultry production and address the challenges posed by antimicrobial resistance and regulatory restrictions on drug use. This abstract encapsulates our commitment to improving poultry health and ensuring food security through innovative and evidence-based strategies.